RESEARCH

Overview

The Growth Factor Mechanobiology Lab investigates an exciting, growing area of mechanobiology: the role of mechanical and extracellular interactions on the activity of growth factors in musculoskeletal tissues. Current research avenues focus on the following key areas: 1) understanding the role of mechanobiological phenomena on the development and degeneration of musculoskeletal tissues, 2) developing insight-based drug delivery platforms to halt the progression of tissue degeneration, 3) developing tissue engineering platforms to repair degenerated musculoskeletal tissues, and 4) spectroscopy-based diagnostics of connective tissue degeneration. The lab consists of a highly multidisciplinary environment with state of the art work performed in the areas of biomechanics, biochemistry, spectroscopy, and biomaterials science. 

Research Projects:

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Force-induced activation of growth factors

Scaffold growth factor conjugation

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Drug Delivery

Targeted delivery of growth factor inhibitors

Reaction diffusion models of growth factors in engineered and native connective tissue

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Intra-articular Raman spectroscopy diagnostics

Recent News

May 2020:  The Albro and Bergholt Labs publish a new Raman paper in Optics Letters

May 2020:  Congratulations to Sung Yeon Kim for receiving the Earle and Mildred Bailey Memorial Award and the Adam Miller Award

May 2020:  Congratulations to the year's Albro Lab graduating seniors:  Sung Yeon Kim, Maggie Wu, and Zhonghao Dai

March 2020:  The Albro Lab is awarded the 2020 MSE Innovation Grant

February 2020:  The Albro and Bergholt Labs present their work on Raman spectroscopy for early OA diagnostics at SPIE Photonics West and the ORS Annual Meeting

February 2020:  Sedat Dogru and Nicholas Simone present abstracts of their work at the 2020 ORS Annual Meeting

January 2020:  Congratulations to Tianbai Wang (Materials Science) and Sedat Dogru (Mechanical Engineering) for passing their qualifying exams