RESEARCH

Overview

The Growth Factor Mechanobiology Lab investigates an exciting, growing area of mechanobiology: the role of mechanical and extracellular interactions on the activity of growth factors in musculoskeletal tissues. Current research avenues focus on two key areas: 1) understanding the role of mechanobiological phenomena on the development and degeneration of musculoskeletal tissues and  2) developing insight-based drug delivery platforms to halt the progression of tissue degeneration, and 3) developing tissue engineering platforms to repair degenerated musculoskeletal tissues. The lab consists of a highly multidisciplinary environment with state of the art work performed in the areas of biomechanics, biochemistry, spectroscopy, and biomaterials science. 

Research Projects:

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Force-induced activation of growth factors

Scaffold growth factor conjugation

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Drug Delivery

Targeted delivery of growth factor inhibitors

Reaction diffusion models of growth factors in engineered and native connective tissue

Recent News

November 2019:  The Albro Lab receives pilot grant from NIH-funded MGH Center for Skeletal Research (CFSR)

November 2019:  The Albro Lab has 3 abstracts accepted to ORS 2020 (2 podium presentations, 1 poster presentation)

October 2019:  Professor Albro gives seminar at Northeastern University on growth factor reaction-diffusion modeling

October 2019:  Albro, Bergholt, and Serio Labs' review paper on Raman spectroscopy accepted in Frontiers in Bioengineering and Biotechnology

October 2019:  Maggie Wu and Eric Dai present posters of their work at the annual UROP Symposium

September 2019:  Albro and Bergholt Labs have their abstract on Raman-based osteoarthritis diagnostics accepted to Photonics West

 

August 2019: Professor Albro presents at CMBBE 2019 on growth factor transport models in tissue engineering

 

July 2019:  The Albro Lab receives NSF Project Grant from Biomechanics and Mechanobiology